Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation.

doi:10.1016/s0027-5107(98)00055-4

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Article

Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation.

Mutation research - 17 Jul 1998

Hama-Inaba H, Wang B, Mori M, Matsushima T, Saitoh T, Takusagawa M, Yamada T, Muto M, Ohyama H

Abstract excerpt

3SB, a mouse thymoma cell line, is one of the most radio-sensitive cells (D0 = 0.3 Gy), and its rapid apoptosis (4 h after 5 Gy irradiation, 90% apoptosis) seems to play a decisive role in enhancing the radiosensitivity. To understand the molecular mechanisms underlying extremely high radiosensit...

Topics

Animals
Antineoplastic Agents
Apoptosis
Daunorubicin
Drug Resistance
Genetic Variation
Methyl Methanesulfonate
Mice
Mitomycin
Mutagens
Radiation Tolerance
Sphingosine
Thymoma
Thymus Neoplasms
Tumor Cells, Cultured
Tumor Suppressor Protein p53

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Open in PubMed

Identifiers

PMID: 9726009
DOI: 10.1016/s0027-5107(98)00055-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9726009-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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