Article
Apoptosis in bone marrow cells of mice with different p53 genotypes after gamma-rays irradiation in vitro.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 1995
Cui Y F, Zhou P K, Woolford L B, Lord B I, Hendry J H, Wang D W
Abstract excerpt
Apoptosis is a physiological phenomenon occurring during embryonic development, T and B cell maturation, and endocrine-induced atrophy. It can be initiated by various agents and has been considered to be related to the expression of the oncosuppressor p53 gene. In this review, p53 gene-targeting mice were used to study the effect of p53 gene status on the induction of apoptosis in bone marrow cells by gamma-ray...
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