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Article

Tracking members of the simian immunodeficiency virus deltaB670 quasispecies population in vivo at single-cell resolution.

Journal of virology - 1 Jan 1998

Reinhart T A, Rogan M J, Amedee A M, Murphey-Corb M, Rausch D M, Eiden L E, Haase A T

Abstract excerpt

Genetically distinct lentiviruses constitute a quasispecies population that can evolve in response to selective forces. To move beyond characterization of the population as a whole to the behavior of individual members, we devised an in situ hybridization approach that uses genotype-specific probes. We used probes that detect simian immunodeficiency viruses (SIV) that differ in sequence in the V1 region of the...

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Identifiers

PMID: 9420206
DOI: 10.1128/JVI.72.1.113-120.1998
PMCID: PMC109355

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