Article
Infection of macaques with a molecular clone, SHIVSF33A2, provides evidence for tissue specific variants.
Journal of medical primatology - 1 Aug 2002
Buckner C M, Gettie A, Tan R C H, Eshetu T, Ratterree M, Blanchard J, Cheng-Mayer C, Harouse J M
Abstract excerpt
Infection of rhesus macaques with chimeric simian-human immunodeficiency viruses (SHIV) is an established model to study acquired immunodeficiency syndrome (AIDS) pathogenesis. Such a controlled system allows for detailed analysis of the molecular determinants of viral pathogenesis in addition to studying host-specific immune responses that modulate disease progression. Furthermore, the use of a pathogenic...
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