Article
Sequences within the herpesvirus-conserved pac1 and pac2 motifs are required for cleavage and packaging of the murine cytomegalovirus genome.
Journal of virology - 1 Jan 1998
McVoy M A, Nixon D E, Adler S P, Mocarski E S
Abstract excerpt
The DNA sequence motifs pac1 [an A-rich region flanked by poly(C) runs] and pac2 (CGCGGCG near an A-rich region) are conserved near herpesvirus genomic termini and are believed to mediate cleavage of genomes from replicative concatemers. To determine their importance in the cleavage process, we c...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
