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Article

Analysis of herpes simplex virus type 1 DNA packaging signal mutations in the context of the viral genome.

Journal of virology - 1 Jan 2010

Tong Lily, Stow Nigel D

Abstract excerpt

The minimal signal required for the cleavage and packaging of replicated concatemeric herpes simplex virus type 1 (HSV-1) DNA corresponds to an approximately 200-bp fragment, Uc-DR1-Ub, spanning the junction of the genomic L and S segments. Uc and Ub occupy positions adjacent to the L and S termini and contain motifs (pac2 and pac1, respectively) that are conserved near the ends of other herpesvirus genomes. We...

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Identifiers

PMID: 19864384
DOI: 10.1128/JVI.01489-09
PMCID: PMC2798400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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