Sequence requirements for DNA rearrangements induced by the terminal repeat of herpes simplex virus type 1 KOS DNA.

doi:10.1128/JVI.64.10.5036-5050.1990

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Article

Sequence requirements for DNA rearrangements induced by the terminal repeat of herpes simplex virus type 1 KOS DNA.

Journal of virology - 1 Oct 1990

Smiley J R, Duncan J, Howes M

Abstract excerpt

We investigated the sequence requirements for the site-specific DNA cleavages and recombinational genome isomerization events driven by the terminal repeat or a sequence of herpes simplex virus type 1 KOS DNA by inserting a series of mutated a sequences into the thymidine kinase locus in the inta...

Topics

Animals
Base Sequence
Chromosome Deletion
DNA, Viral
Genes, Viral
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Recombination, Genetic
Repetitive Sequences, Nucleic Acid
Simplexvirus
Thymidine Kinase
Vero Cells

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