Article
GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population.
Genetics and molecular research : GMR - 29 Jan 2016
Khabaz M N, Nedjadi T, Gari M A, Al-Maghrabi J A, Atta H M, Bakarman M, Gazzaz Z J
Abstract excerpt
The enzyme glutathione S-transferase Mu 1 (GSTM1) is encoded by the GSTM1 gene. Polymorphisms in GSTM1 affect the detoxifying function of the enzyme variants. This forms the basis of the debate about the impact of the GSTM1 null/present genotype on colorectal carcinoma risk. We tested the potential influence of GSTM1 polymorphisms on the development of colorectal cancer. DNA extracted from 83 samples taken from...
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