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Article

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.

1 Nov 1997

Abstract excerpt

This study was performed to test the hypothesis that cytotoxic T lymphocyte (CTL) selection of hepatitis C virus (HCV) escape variants plays a role in HCV persistence. The peripheral blood CTL responsiveness of patients with well-established chronic hepatitis C to a panel of 10 prototype HCV peptides (genotype 1a) was compared with the corresponding sequences encoded by the infecting viruses in each patient....

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Identifiers

PMID: 9410918
DOI: 10.1172/jci119778

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.PMID 9410918Read ↗

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