Article
Hepatitis B virus (HBV) sequence variation of cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection.
The Journal of clinical investigation - 1 Sept 1995
Rehermann B, Pasquinelli C, Mosier S M, Chisari F V
Abstract excerpt
It has been suggested that immune selection pressure exerted by the cytotoxic T lymphocyte (CTL) response could be responsible for viral persistence during chronic hepatitis B virus infection. To address this question, in the current study we compared the DNA and amino acid sequences of, and the...
Topics
- Acute Disease
- Adult
- Aged
- Amino Acid Sequence
- Base Sequence
- Chronic Disease
- DNA Primers
- Epitopes
- Female
- Genetic Variation
- HLA-A2 Antigen
- Hepatitis B
- Hepatitis B Antigens
- Hepatitis B virus
- Humans
- Male
- Middle Aged
- Molecular Sequence Data