Article
A prothrombin gene mutation is significantly associated with venous thrombosis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1997
Kapur R K, Mills L A, Spitzer S G, Hultin M B
Abstract excerpt
This case-control study examined the prevalence of a prothrombin gene mutation in the 3'-untranslated region (UTR) first reported by Poort et al in Dutch subjects with a history of venous thrombosis and in matched control subjects without a history of thrombosis. We tested the hypothesis that the presence of the 3'UTR prothrombin mutation would convey a higher risk of venous or arterial thrombosis and therefore...
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