Article
Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism.
American journal of hematology - 1 Dec 2002
Folsom Aaron R, Cushman Mary, Tsai Michael Y, Heckbert Susan R, Aleksic Nena
Abstract excerpt
Case-control studies have indicated increased risk of venous thrombosis associated with the prothrombin gene G20210A polymorphism and with elevated plasma prothrombin levels. We sought to confirm these results in a prospective population-based study of 21,690 persons. We measured G20210A and prothrombin antigen on pre-event blood samples of 302 participants who developed venous thromboembolism (VTE) and 626...
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