Article
Heterozygous Prothrombin Mutation-Associated Thrombophilia.
Thrombosis and haemostasis - 1 Jan 2025
Wu Xi, Li Lei, Lu Zhengjing, Hu Xiaobo, Lu Yeling, Liu Yu, Xu Guanqun, Ding Qiulan, Wang Xuefeng, Wu Wenman, Jin Peipei, Dai Jing
Abstract excerpt
BACKGROUND: Venous thromboembolism (VTE) is predisposed by thrombotic mutations in patients with hereditary thrombophilia. Although prothrombin deficiencies caused by homozygous or compound heterozygous mutations are associated with bleeding diathesis, rare cases have shown a correlation between heterozygous prothrombin mutations and thrombosis. MATERIALS AND METHODS: We surveyed genetic variants involved in...
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