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Article

Use of a two-hybrid system to identify mutations in Max that confer increased affinity for Myc.

DNA and cell biology - 1 Nov 1997

Wang H, Van Den Bergh F, Spencer E, Wilcox K, Herman T

Abstract excerpt

A yeast two-hybrid system was used to identify mutants of Max that exhibit an increased affinity for Myc. Truncated forms of the Max helix-loop-helix/leucine zipper motif (HLH/Zip) were first expressed in a two- hybrid system in which the bait protein was the HLH/Zip motif of Myc. Deletion of amino acids both amino-terminal and carboxy-terminal to the leucine zipper of Max reduced Myc/Max heterodimer formation as...

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Source

Identifiers

PMID: 9407000
DOI: 10.1089/dna.1997.16.1277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Use of a two-hybrid system to identify mutations in Max that confer increased affinity for Myc.PMID 9407000Read ↗

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