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Article

Structural and thermodynamical characterization of the complete p21 gene product of Max.

Biochemistry - 27 Sept 2005

Naud Jean-François, McDuff François-Olivier, Sauvé Simon, Montagne Martin, Webb Bradley A, Smith Steven P, Chabot Benoit, Lavigne Pierre

Abstract excerpt

The b-HLH-LZ family of transcription factors contains numerous proteins including the Myc and Mad families of proteins. Max heterodimerizes with other members to bind the E-Box DNA sequence in target gene promoters. Max is the only protein in this network that recognizes and binds E-Box DNA sequences as a homodimer in vitro and represses transcription of Myc target genes in vivo. Key information such as the...

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Source

Identifiers

PMID: 16171389
DOI: 10.1021/bi0500729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural and thermodynamical characterization of the complete p21 gene product of Max.PMID 16171389Read ↗

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