Article
Differential patterns of DNA binding by myc and max proteins.
Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1993
Prochownik E V, VanAntwerp M E
Abstract excerpt
c-myc, N-myc, and L-myc genes are subject to highly variable degrees of tissue-specific regulation. Their aberrant expression has also been implicated in the pathogenesis of a variety of malignant tumors. The recently identified max protein dimerizes with c-myc to promote its sequence-specific DN...
Topics
- Base Sequence
- Basic-Leucine Zipper Transcription Factors
- Cell-Free System
- Cross-Linking Reagents
- DNA-Binding Proteins
- Gene Expression Regulation, Neoplastic
- Genetic Variation
- Glutaral
- Macromolecular Substances
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Phosphorylation
- Protein Conformation
- Protein Processing, Post-Translational
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins c-myc
- Recombinant Proteins
- Reticulocytes