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Article

Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs.

FEBS letters - 9 Apr 2004

Kovalovsky Damian, Paez Pereda Marcelo, Labeur Marta, Renner Ulrich, Holsboer Florian, Stalla Günter K, Arzt Eduardo

Abstract excerpt

Nur77 and Nurr1 are critical for proopiomelanocortin (POMC) regulation by corticotrophin releasing hormone (CRH) in corticotrophs. We analyze the regulation and activity of Nur77 by interleukin (IL)-1 in AtT-20 corticotrophic cells and its consequences on POMC regulation. IL-1 induces Nur77 and n...

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Share to Corticotropin-Releasing Hormone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Cytoplasmic and Nuclear

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Source

Identifiers

PMID: 15063754
DOI: 10.1016/S0014-5793(04)00303-5

Genes

POMC
CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15063754-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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