Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.

Proceedings of the National Academy of Sciences of the United States of America - 23 Dec 1997

Schwarz M, Alvarez-Bolado G, Urbánek P, Busslinger M, Gruss P

Abstract excerpt

The development of two major subdivisions of the vertebrate nervous system, the midbrain and the cerebellum, is controlled by signals emanating from a constriction in the neural primordium called the midbrain/hindbrain organizer (Joyner, A. L. (1996) Trends Genet. 12, 15-201). The closely related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Embryonic and Fetal Development
Share to Gene Targeting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Mutation

Share to Nuclear Proteins

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 9405645
DOI: 10.1073/pnas.94.26.14518
PMCID: PMC25040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9405645-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.PMID 9405645Read ↗

Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.Semantic proximity Read ↗

Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.Semantic proximity Read ↗

Pax2/5 and Pax6 subdivide the early neural tube into three domains.Semantic proximity Read ↗

Ancestral Regulatory Mechanisms Specify Conserved Midbrain Circuitry in Arthropods and VertebratesSemantic proximity Read ↗

Cerebellar development in the absence of Gbx function in zebrafish.Semantic proximity Read ↗

Fkh5-deficient mice show dysgenesis in the caudal midbrain and hypothalamic mammillary body.Semantic proximity Read ↗

The caudal limit of Otx2 expression positions the isthmic organizer.Semantic proximity Read ↗

A threshold requirement for Gbx2 levels in hindbrain development.Semantic proximity Read ↗

Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins.Semantic proximity Read ↗

Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function.Semantic proximity Read ↗

Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants.Semantic proximity Read ↗

Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.