Article
Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.
Development (Cambridge, England) - 1 Sept 2000
Bouchard M, Pfeffer P, Busslinger M
Abstract excerpt
Pax2 and Pax5 arose by gene duplication at the onset of vertebrate evolution and have since diverged in their developmental expression patterns. They are expressed in different organs of the mouse embryo except for their coexpression at the midbrain-hindbrain boundary (MHB), which functions as an organizing center to control midbrain and cerebellum development. During MHB development, Pax2 expression is initiated...
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