Article
The gene encoding the elongation factor P protein is essential for viability and is required for protein synthesis.
The Journal of biological chemistry - 19 Dec 1997
Aoki H, Dekany K, Adams S L, Ganoza M C
Abstract excerpt
Elongation factor P (EFP) is a protein that stimulates the peptidyltransferase activity of fully assembled 70 S prokaryotic ribosomes and enhances the synthesis of certain dipeptides initiated by N-formylmethionine. This reaction appears conserved throughout species and is promoted in eukaryotic cells by a homologous protein, eIF5A. Here we ask whether the Escherichia coli gene encoding EFP is essential for cell...
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