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Escherichia coli mrsC is an allele of hflB, encoding a membrane-associated ATPase and protease that is required for mRNA decay.

Journal of bacteriology - 1 Apr 1998

Wang R F, O'Hara E B, Aldea M, Bargmann C I, Gromley H, Kushner S R

Abstract excerpt

The mrsC gene of Escherichia coli is required for mRNA turnover and cell growth, and strains containing the temperature-sensitive mrsC505 allele have longer half-lives than wild-type controls for total pulse-labeled and individual mRNAs (L. L. Granger et al., J. Bacteriol. 180:1920-1928, 1998). T...

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Mutation
Molecular Sequence Data
Base Sequence
Alleles
Amino Acid Sequence
Cloning, Molecular

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Escherichia coli

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PMID: 9537394
DOI: 10.1128/JB.180.7.1929-1938.1998
PMCID: PMC107109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9537394-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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