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Article

Identification of Substrates of Cytoplasmic Peptidyl-Prolyl Cis/Trans Isomerases and Their Collective Essentiality in Escherichia Coli.

International journal of molecular sciences - 13 Jun 2020

Klein Gracjana, Wojtkiewicz Pawel, Biernacka Daria, Stupak Anna, Gorzelak Patrycja, Raina Satish

Abstract excerpt

Protein folding often requires molecular chaperones and folding catalysts, such as peptidyl-prolyl cis/trans isomerases (PPIs). The Escherichia coli cytoplasm contains six well-known PPIs, although a requirement of their PPIase activity, the identity of their substrates and relative enzymatic contribution is unknown. Thus, strains lacking all periplasmic and one of the cytoplasmic PPIs were constructed....

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Identifiers

PMID: 32545723
DOI: 10.3390/ijms21124212
PMCID: PMC7353009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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