Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clotting factor IX levels in C/EBP alpha knockout mice.

British journal of haematology - 1 Dec 1997

Davies N, Austen D E, Wilde M D, Darlington G J, Brownlee G G

Abstract excerpt

Previous studies have indicated that C/EBP alpha is involved in the regulation of factor IX and mutations of a C/EBP recognition element in the factor IX promoter result in haemophilia B. We now report that mice homozygous for the deletion of the c/ebp alpha gene are significantly deficient in factor IX transcription.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Factor IX
Share to EBP gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mutation

Share to RNA, Messenger

Share to Transcription, Genetic

Source

Identifiers

PMID: 9401069
DOI: 10.1046/j.1365-2141.1997.4603263.x

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Clotting factor IX levels in C/EBP alpha knockout mice.PMID 9401069Read ↗

Novel hemophilia B mouse models exhibiting a range of mutations in the Factor IX gene.Semantic proximity Read ↗

Disruption of a C/EBP binding site in the factor IX promoter is associated with haemophilia B.Semantic proximity Read ↗

Gene targeting in hemostasis. factor XI.Semantic proximity Read ↗

Creation of a mouse expressing defective human factor IX.Semantic proximity Read ↗

Gene targeting of tissue factor, factor X, and factor VII in mice: their involvement in embryonic development.Semantic proximity Read ↗

A Coagulation Factor IX-Deficient Mouse Model for Human Hemophilia BSemantic proximity Read ↗

Characterization of a genetically engineered mouse model of hemophilia A with complete deletion of the F8 gene.Semantic proximity Read ↗

Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.