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Article

Genomewide transmission/disequilibrium testing--consideration of the genotypic relative risks at disease loci.

American journal of human genetics - 1 Dec 1997

Camp N J

Abstract excerpt

Genomewide association studies are set to become the tool of the future for detection of small-effect genes in complex diseases. It will therefore be necessary to calculate sufficient sample sizes with which to perform them. In this paper I illustrate how to calculate the required number of families for general genotypic relative risks (GRRs). I show the superior sensitivity of the genomewide association study...

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Identifiers

PMID: 9399906
DOI: 10.1086/301648
PMCID: PMC1716090

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