Article
Pairwise linkage disequilibrium under disease models.
European journal of human genetics : EJHG - 1 Feb 2007
Schrodi Steven J, Garcia Veronica E, Rowland Charley, Jones Hywel B
Abstract excerpt
Many genetic studies of disease association rely heavily on linkage disequilibrium (LD) patterns between pairs of markers to detect susceptibility markers. This is true of large-scale positional mapping approaches as well as haplotype construction, selection of tagging single-nucleotide polymorphisms and population genetic analyses. Whereas the distribution of different LD measures has been investigated for...
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