Article
Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity.
The Journal of clinical endocrinology and metabolism - 1 Dec 1997
Urhammer S A, Fridberg M, Sørensen T I, Echwald S M, Andersen T, Tybjaerg-Hansen A, Clausen J O, Pedersen O
Abstract excerpt
Our objective was to investigate whether genetic variants of the uncoupling protein 1 (UCP1) gene are associated with juvenile-onset obesity or alterations in weight gain and insulin sensitivity in young healthy Caucasians. Single-strand conformation polymorphism and heteroduplex analysis of the coding region of the UCP1 gene was performed in 56 subjects randomly selected at the draft board examination from a...
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