Article
The reduction of Calpain-10 expression is associated with risk polymorphisms in obese children.
Gene - 1 Mar 2013
Mendoza-Lorenzo Patricia, Salazar Ana Maria, Cortes-Arenas Eladio, Saucedo Renata, Taja-Chayeb Lucia, Flores-Dorantes Maria T, Pánico Pablo, Sordo Monserrat, Ostrosky-Wegman Patricia
Abstract excerpt
Excessive weight gain and obesity are major public health concerns. Childhood obesity is growing at an alarming rate. Polymorphisms in the Calpain-10 gene and the reduced expression of this gene in muscle cells and adipocytes have been associated with an increased risk of type 2 diabetes mellitus in several populations. In the present study, we explored the contribution of Calpain-10 in the development of...
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