Article
A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population.
The Journal of clinical endocrinology and metabolism - 1 Mar 2001
Dalgaard L T, Sørensen T I, Drivsholm T, Borch-Johnsen K, Andersen T, Hansen T, Pedersen O
Abstract excerpt
Variability of the uncoupling protein 3 (UCP3) promoter has been associated with increased body mass index (BMI) and altered lipid profiles. Here we tested the hypothesis that variation of the UCP3 promoter is associated with either juvenile or maturity-onset obesity or body weight change over a 26-yr follow-up among Danish subjects. Mutation screening of approximately 1 kb 5' upstream of the UCP3 gene revealed...
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