Article
Differential in vivo regulation of steroid hormone receptor activation by Cdc37p.
Molecular biology of the cell - 1 Dec 1997
Fliss A E, Fang Y, Boschelli F, Caplan A J
Abstract excerpt
The CDC37 gene is essential for the activity of p60(v-src) when expressed in yeast cells. Since the activation pathway for p60(v-src) and steroid hormone receptors is similar, the present study analyzed the hormone-dependent transactivation by androgen receptors and glucocorticoid receptors in yeast cells expressing a mutant version of the CDC37 gene. In this mutant, hormone-dependent transactivation by androgen...
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