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Article

The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest.

FEBS letters - 4 Feb 2000

Abbas-Terki T, Donzé O, Picard D

Abstract excerpt

The molecular chaperone Cdc37 is thought to act in part as a targeting subunit of the heat-shock protein 90 (Hsp90) chaperone complex. We demonstrate here that Cdc37 is required for activity of the kinase Ste11 in budding yeast. A cdc37 mutant strain is defective in Ste11-mediated pheromone signaling and in accumulation and functional maturation of the constitutively active Ste11 version Ste11DeltaN. Moreover,...

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Source

Identifiers

PMID: 10664467
DOI: 10.1016/s0014-5793(00)01134-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest.PMID 10664467Read ↗

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Comparative analysis of the impact of Heat shock protein 90 kDa or Cdc37 mutation on the yeast proteome.Semantic proximity Read ↗

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