Article
Analysis of the transcriptional program induced by Raf in epithelial cells.
Genes & development - 15 Apr 2001
Schulze A, Lehmann K, Jefferies H B, McMahon M, Downward J
Abstract excerpt
Activation of the Raf/MAP kinase pathway is a critical event in tumorigenesis induced by RAS and other oncogenes, a major role of this signaling system being the regulation of cellular transcription factors. To address the contribution of MAP kinase mediated transcriptional changes to the transfo...
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