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Article

Modeling linkage disequilibrium between a polymorphic marker locus and a locus affecting complex dichotomous traits in natural populations.

Genetics - 1 Aug 2001

Luo Z W, Wu C I

Abstract excerpt

Linkage disequilibrium is an important topic in evolutionary and population genetics. An issue yet to be settled is the theory required to extend the linkage disequilibrium analysis to complex traits. In this study, we present theoretical analysis and methods for detecting or estimating linkage disequilibrium (LD) between a polymorphic marker locus and any one of the loci affecting a complex dichotomous trait on...

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Identifiers

PMID: 11514462
DOI: 10.1093/genetics/158.4.1785
PMCID: PMC1461768

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