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Article

Intracellular targeting of truncated secretory peptides in the mammalian heart and brain.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2006

Brun Cécile, Philip-Couderc Pierre, Raggenbass Mario, Roatti Angela, Baertschi Alex J

Abstract excerpt

Secretory polypeptides are vital for nervous system function, sleep, reproduction, growth, and metabolism. Ribosomes scanning the 5'-end of mRNA usually detect the first AUG site for initiating translation. The nascent propeptide chain is then directed via a signal-peptide into the endoplasmic reticulum, processed through the Golgi stacks, and packaged into secretory vesicles. By expressing prepropeptide-EGFP...

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PMID: 16443679
DOI: 10.1096/fj.05-4338fje

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NPY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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