Article
Computer simulations of prebiotic evolution.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 1997
Abkevich V I, Gutin A M, Shakhnovich E I
Abstract excerpt
This paper is a review of our previous work on the field of possible ways of prebiotic evolution. We propose an algorithm providing sequences of model proteins with rapid folding into a given native conformation. Thermodynamical analysis shows that the increase in speed is matched by an increase in stability: the evolved sequences are much more stable in their native conformation than the initial random sequence....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.