Theory for protein mutability and biogenesis.

doi:10.1073/pnas.87.2.638

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Article

Theory for protein mutability and biogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jan 1990

Lau K F, Dill K A

Abstract excerpt

Using an elementary physical model for protein folding, of self-avoiding short copolymer chains on two-dimensional square lattices, we address two questions regarding the evolution and origins of globular proteins. (i) How will protein native structures and stabilities be affected by single-and d...

Topics

Amino Acid Sequence
Models, Biological
Models, Genetic
Models, Structural
Mutation
Protein Conformation
Proteins
Thermodynamics

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