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Article

Permutation testing in the presence of polygenic variation.

Genetic epidemiology - 1 May 2015

Abney Mark

Abstract excerpt

This article discusses problems with and solutions to performing valid permutation tests for quantitative trait loci in the presence of polygenic effects. Although permutation testing is a popular approach for determining statistical significance of a test statistic with an unknown distribution--for instance, the maximum of multiple correlated statistics or some omnibus test statistic for a gene, gene-set, or...

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Identifiers

PMID: 25758362
DOI: 10.1002/gepi.21893
PMCID: PMC4634896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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