Article
Heredity Indexes for Estimating Heritability Using Known and Unknown Family Data Based on the Model of Polygenic Inheritance.
Computational and mathematical methods in medicine - 1 Jan 2020
Liu Hui
Abstract excerpt
OBJECTIVE: To establish a model for estimating genetic risk using known and unknown family data. METHODS: Four simulated datasets were generated for four paternal and maternal chromosomes. The simulated data for children were generated from the parental data according to the Mendelian law. The correlation coefficient between the children's and paternal data was calculated, and 2R was defined as the heredity index...
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