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Article

Incorporating Polygenic Risk Scores in the ACE Twin Model to Estimate A-C Covariance.

Behavior genetics - 1 May 2021

Dolan Conor V, Huijskens Roel C A, Minică Camelia C, Neale Michael C, Boomsma Dorret I

Abstract excerpt

The assumption in the twin model that genotypic and environmental variables are uncorrelated is primarily made to ensure parameter identification, not because researchers necessarily think that these variables are uncorrelated. Although the biasing effects of such correlations are well understood, a method to estimate these parameters in the twin model would be useful. Here we explore the possibility of relaxing...

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PMID: 33523349
DOI: 10.1007/s10519-020-10035-7
PMCID: PMC8093156

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ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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