Article
A simple combinatorial method for calculating genetic risks.
Clinical genetics - 1 Jan 2000
Maag U R, Gold R J
Abstract excerpt
A method is presented whereby genetic counsellors can calculate genetic risks in a wide variety of circumstances using only arithmetics. The method is general in that it can handle such information as gene frequency, mutation rate, mode of inheritance, penetrance, pedigree to which the consultand belongs, phenotype of the consultand and his relatives, biochemical findings, etc. Each of the possible combinations...
Topics
- Computers
- Gene Frequency
- Genetic Counseling
- Genetic Techniques
- Genotype
- Humans
- Mathematics
- Mutation
- Pedigree
- Phenotype
- Prenatal Diagnosis
- Risk