Principled measures and estimates of trait polygenicity.

Abstract excerpt

While quantitative and statistical genetic studies often invoke the "polygenicity" of traits and sometimes quantify it, the meaning of the term is not always clear. We propose a principled definition of polygenicity that encompasses a range of measures. We show that these measures satisfy mathematical properties that are sensible and, conversely, that measures that satisfy these properties meet our definition. We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genome-Wide Association Study
• Share to Models, Genetic
• Share to Multifactorial Inheritance