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Article

Dimerization properties of mutant thyroid hormone beta-receptors with auxiliary proteins.

The Journal of endocrinology - 1 Sept 1997

Tagami T, Nakamura H, Sasaki S, Miyoshi Y, Nakao K

Abstract excerpt

Hormonal responsiveness in peripheral tissues is variable in patients with resistance to thyroid hormone (RTH). One cause of this may be differential interaction of RTH mutants of thyroid hormone receptor beta (TR beta) with TR auxiliary proteins (TRAPs). We used gel shift mobility assays to examine the interaction of wild-type and mutant TR beta s with retinoid X receptors (RXRs) and endogenous TRAPs. Some...

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PMID: 9379130
DOI: 10.1677/joe.0.1540523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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