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Article

The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness.

Mechanisms of development - 1 Aug 1997

Heymer J, Kuehn M, Rüther U

Abstract excerpt

We have investigated the expression of left/right (L/R) asymmetry markers, nodal and lefty, in the situs inversus mouse mutant Fused toes (Ft). Both genes exhibited bilateral expression in the lateral plate mesoderm (LPM) at developmental stages whereas in wildtype embryos these genes were found to be expressed exclusively in the left LPM. Inspection of tail location and primitive heart tube looping, structures...

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PMID: 9376323
DOI: 10.1016/s0925-4773(97)00084-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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