Handed asymmetry in the mouse: understanding how things go right (or left) by studying how they go wrong.

Abstract excerpt

All vertebrates have characteristic asymmetries along the left/right axis. The positioning of asymmetric visceral organs is highly conserved evolutionarily and disruptions in left/right patterning can lead to severe morphological defects, demonstrating the importance of regulation of left/right developmental asymmetries. Our understanding of vertebrate left/right pattern formation has been advanced by studying...

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