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Article

MK-801 potentiates antidystonic effects of clozapine but not of haloperidol in mutant dystonic hamsters.

Brain research - 26 Sept 1997

Richter A, Löscher W

Abstract excerpt

The interaction of nigrostriatal dopamine and corticostriatal glutamate plays a critical role in motor output. Recent studies in mutant dystonic hamsters (dt[sz]), an animal model of idiopathic generalized dystonia, revealed antidystonic effects of both N-methyl-D-aspartate (NMDA) receptor antagonists, such as dizocilpine (MK-801), and of neuroleptics, such as haloperidol and clozapine. Whereas the neuroleptics...

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Identifiers

PMID: 9374198
DOI: 10.1016/s0006-8993(97)00720-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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