Article
Emergence of oligodendrocytes from human neural spheres.
Journal of neuroscience research - 15 Oct 1997
Murray K, Dubois-Dalcq M
Abstract excerpt
To study the development of human oligodendrocyte precursors (OP), we expanded human embryonic brain-derived neural precursors into spheres with basic fibroblast growth factor (FGF2). Over 90% of the cells in the expanded spheres were precursors coexpressing nestin and the polysialylated (PSA) form of NCAM. The remaining cells were mostly astrocytes and neuronal cells located at the periphery of the floating...
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