Article
Phenotypic and morphological characterization of in vitro oligodendrogliogenesis.
Stem cells and development - 1 Apr 2008
Mokrý J, Karbanová J, Filip S, Cízková D, Pazour J, English D
Abstract excerpt
The neurosphere assay has been used to maintain neural progenitor cells (NPCs) in the undifferentiated state. These cells are multipotent and gave rise to neurons and glial cells. Here we show that within 10 days of culture, neurospheres contained precursors and differentiated progeny of all three major central nervous system (CNS) cell lineages and these occupied distinct zones. The microenvironment of the inner...
Topics
- Animals
- Antigens
- Astrocytes
- Cell Differentiation
- Cells, Cultured
- Glial Fibrillary Acidic Protein
- Mice
- Mice, Inbred Strains
- Oligodendroglia
- Phenotype
- Proteoglycans
- Spheroids, Cellular
- Tubulin