Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sin mutations of histone H3: influence on nucleosome core structure and function.

Molecular and cellular biology - 1 Dec 1997

Kurumizaka H, Wolffe A P

Abstract excerpt

Sin mutations in Saccharomyces cerevisiae alleviate transcriptional defects that result from the inactivation of the yeast SWVI/SNF complex. We have investigated the structural and functional consequences for the nucleosome of Sin mutations in histone H3. We directly test the hypothesis that mutations in histone H3 leading to a SWI/SNF-independent (Sin) phenotype in yeast lead to nucleosomal destabilization. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Fungal Proteins
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Plasmids

Share to Recombinant Proteins

Share to Saccharomyces cerevisiae

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 9372928
DOI: 10.1128/MCB.17.12.6953
PMCID: PMC232553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sin mutations of histone H3: influence on nucleosome core structure and function.PMID 9372928Read ↗

Effects of Sin- versions of histone H4 on yeast chromatin structure and function.Semantic proximity Read ↗

Sin mutations alter inherent nucleosome mobility.Semantic proximity Read ↗

Analysis of a mutant histone H3 that perturbs the association of Swi/Snf with chromatin.Semantic proximity Read ↗

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.Semantic proximity Read ↗

Identification of histone mutants that are defective for transcription-coupled nucleosome occupancy.Semantic proximity Read ↗

Histone Sin mutations promote nucleosome traversal and histone displacement by RNA polymerase II.Semantic proximity Read ↗

Dispersed mutations in histone H3 that affect transcriptional repression and chromatin structure of the CHA1 promoter in Saccharomyces cerevisiae.Semantic proximity Read ↗

Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae.Semantic proximity Read ↗

Contributions of histone H3 nucleosome core surface mutations to chromatin structures, silencing and DNA repair.Semantic proximity Read ↗

Simulations of SIN mutations and histone variants in human nucleosomes reveal altered protein-DNA and core histone interactions.Semantic proximity Read ↗

A systematic mutational analysis of a histone H3 residue in budding yeast provides insights into chromatin dynamics.Semantic proximity Read ↗

Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.