Article
Development and utilization of the rat lymphocyte hprt mutation assay.
Mutation research - 1 Oct 1997
Aidoo A, Morris S M, Casciano D A
Abstract excerpt
Much of the recent progress in the field of genetic toxicology has come from an increased understanding of the molecular and cellular biology of the mammalian organism. Most prominent has been the ability to detect and quantify somatic mutation and relate the nature of the mutation to the specific type of chemical damage. Building upon the foundation of the human lymphocyte hypoxanthine guanine phosphoribosyl...
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