Article
The dual pathogenesis of paroxysmal nocturnal hemoglobinuria.
Current opinion in hematology - 1 Mar 1996
Luzzatto L, Bessler M
Abstract excerpt
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired blood disease with distinct and rather peculiar characteristics that have puzzled hematologists for more than a century. PNH cells are deficient in a set of membrane proteins that have in common a glycolipid anchor. We refer to this combination of deficiencies as the PNH abnormality or the PNH phenotype. Biochemical analysis has recently made it possible to...
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