Article
Structural comparison of the enzymatically active and inactive forms of delta crystallin and the role of histidine 91.
Biochemistry - 18 Nov 1997
Abu-Abed M, Turner M A, Vallée F, Simpson A, Slingsby C, Howell P L
Abstract excerpt
The major soluble protein component of avian and reptilian eye lenses, delta crystallin, is highly homologous to the urea cycle enzyme, argininosuccinate lyase (ASL). In duck lenses there are two highly homologous delta crystallins, termed delta I and delta II, that are 94% identical in amino aci...
Topics
- Amino Acid Sequence
- Animals
- Argininosuccinate Lyase
- Binding Sites
- Conserved Sequence
- Crystallins
- Crystallography, X-Ray
- Ducks
- Histidine
- Hydrogen Bonding
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Recombinant Proteins
- Sequence Homology, Amino Acid
- Turkey